Mechanism: against herpes simplex types 1 and 2, Varicella Zoster virus, Epstein-Barr virus and Cytomegalo virus. The enzyme thymidine kinase(TK) in virus-infected but not uninfected cells initiates the activation of acyclovir into the triphosphate. This interferes with viral DNA polymerase and inhibits viral duplication.
Dosage:Herpes Simplex Initial therapy : 200 mg 5 times daily for 10 days. Herpes Simplex Chronic Supressive therapy 200400 mg 2 to 4 times daily for 12 months. Herpes Zoster : 800 mg 5 times daily at 4 hours intervals for 7-10 days.Varicella Zoster 20 mg/kg (not more than 800 mg) 4 times daily for 5 days. Children: 6 months to 12 years 500 mg/m2 infused over 1 hour every 8 hours for 7 days. Severe Episodes of Herpes Genitalis 5mg/kg infused over 1 hour every 8 hours for 5 da s Children: Under 12 ears 250m m2 infused over 1 hour every 8 hours for 5 days.
Infusion
أربعة مرات يوميا
Mechanism: against herpes simplex types 1 and 2, Varicella Zoster virus, Epstein-Barr virus and Cytomegalo virus. The enzyme thymidine kinase(TK) in virus-infected but not uninfected cells initiates the activation of acyclovir into the triphosphate. This interferes with viral DNA polymerase and inhibits viral duplication.
Dosage:Herpes Simplex Initial therapy : 200 mg 5 times daily for 10 days. Herpes Simplex Chronic Supressive therapy 200400 mg 2 to 4 times daily for 12 months. Herpes Zoster : 800 mg 5 times daily at 4 hours intervals for 7-10 days.Varicella Zoster 20 mg/kg (not more than 800 mg) 4 times daily for 5 days. Children: 6 months to 12 years 500 mg/m2 infused over 1 hour every 8 hours for 7 days. Severe Episodes of Herpes Genitalis 5mg/kg infused over 1 hour every 8 hours for 5 da s Children: Under 12 ears 250m m2 infused over 1 hour every 8 hours for 5 days.
Note: All the provided information about this drug does not substitute for consulting a doctor.